Antifungal Potential of Myco-molecules of Coprinopsis cinerea (Schaeff) S. Gray s.lat. against Fusarium spp

Abstract

Inky cap mushroom (Coprinus sp) possesses vital antifungal properties against the major wilt causing pathogens of banana, tomato and chilli. Wilt disease caused by Fusarium oxysporum f. sp. cubense in banana, F. o. f. sp. lycopersici in tomato and F.brachygibbosum in chilli were obtained and the antifungal activities of Coprinus cinerea was assessed. Methanolic extract from the fruiting bodies of inky cap C. cinerea consisted of molecules which could inhibit the growth of Fusarium spp at 2000 ppm. Results showed 54.5, 52.2 and 51.1 per cent of mycelia inhibition of F. oxysporum f. sp. cubense, F. o. f. sp. lycopersici and F. brachygibbosum, respectively when the methanolic extract of C. cinerea was used in agar wells in petri dishes. GC-MS analysis of the methanolic extract of the fruiting bodies of inky cap indicated the presence of 9 different compounds viz., formic acid, 2-propenyl ester; acetic acid; D-alanine; N-propargyloxycarbonyl-; isohexyl ester; 4H-Pyran-4-one; 2,3-dihydro-3,5-dihydroxy-6-methyl-; n-hexadecanoic acid; octasiloxane; 1,1,3,3,5,5,7,7,9,9,11,11,13,13,15,15-hexadecamethyl-; 2,7-diphenyl-1,6-dioxopyridazino [4,5:2’,3’] pyrrolo[4’,5’-d]pyridazine; squalene and 2-Nonadecanone 2,4-dinitrophenylhydrazine. Among these compounds, formic acid, 2-propenyl ester, acetic acid; n-hexadecanoic acid; 2,7-diphenyl-1,6-dioxopyridazino [4,5:2’,3’] pyrrolo[4’,5’-d]pyridazine; squalene; 2-nonadecanone 2,4-dinitrophenylhydrazine are have been reported to possess antifungal activities.

DOI

https://doi.org/10.29321/MAJ.2018.000100

Pages

56 - 60

Creative Commons

Copyright

© The Author(s), 2026. Published by Madras Agricultural Students' Union in Madras Agricultural Journal (MAJ). This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited by the user.

Keywords